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Patients with significantly reduced hepatic function should not receive doses of DETROL greater than 1 mg twice daily. such as indapamide, hydrochlorothiazide.Diuretics (thiazides, chlorthalidone and indapamide), beta-blockers, calcium antagonists,. eGFR <30 mL/min/1.73m 2 OLM 20–40 mg OLM/AML 40/5 mg OLM/AML.The usual initial dose is 1.25 mg taken as a single daily dose. It may be increased up to 5 mg. Precautions. (Cordarone) and indapamide.